Pharmacology (PHCL)

PHCL 2020:   Envir. Hlth Perspectives  
Biomolecular Sciences  
A survey course emphasizing environmental health issues, such as overpopulation, resource management, environmental degradation, and pollution. The course is designed for nonpharmacy majors. Prerequisite requirements for this course may also be satisfied by equivalent course work as approved by the department.  
3 credits  
Prerequisites
min grade of C in BISC 1020 and BISC 1040.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3400:   Animal Cells: Testing New Drug  
Biomolecular Sciences  
The aim of this course is to provide an introduction to the multiple biochemical and molecular approaches that explain how cell reacts to foreign organic agents without introducing the names of too many specific drugs. It is intended to develop the subject from the point of view of pharmacologists who are working at the molecular level and trying to understand the problems of drug-cell interactions. Parts of the discussion will be a repetition for some students. However, lectures are concentrated on key theories and novel approaches that hone in on a variety of contemporary interdisciplinary fields, which define pharmacology.  
1 credit  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3411:   Human Pathophysiology I  
Biomolecular Sciences  
The students will understand the consequences of disease on normal physiology. An in-depth study of the pathophysiology condition will equip the students to assess multi-organ system dysfunction. These basic understandings will enable the students to progress through the curriculum with a knowledge and analytical base necessary to excel during their practice experiences.  
3 credits  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture/Lab
  
Course Fees:
$85.00
  
PHCL 3412:   Human Pathophysiology II  
Biomolecular Sciences  
The students will understand the consequences of disease on normal physiology. An in-depth study of the pathophysiology condition will equip the students to assess multi-organ system dysfunction. These basic understandings will enable the students to progress through the curriculum with a knowledge and analytical base necessary to excel during their practice experiences.  
3 credits  
Prerequisites
min grade of C in PHCL 3411 and 24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture/Lab
  
Course Fees:
$75.00
  
PHCL 3450:   Nutritional Pharmacology  
Biomolecular Sciences  
Nutritional issues of concern to pharmacists, including the popular use of nutritional supplements for physiological enhancement and disease prevention, drug-nutrient interactions, therapeutic implications for nutritional pharmacology, and product availability.  
3 credits  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3460:   Immunological Basis for Tx.  
Biomolecular Sciences  
This course will provide students with an overview of how immune system works and its involvement in health and disease.  
3 credits  
Prerequisites
min grade of C in BISC 1620 and BISC 1630 and 24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3470:   Intro. to Envir. Toxicology  
Biomolecular Sciences  
Introduction to chemical nature and reactions of toxic substances; their origins and uses; and the aspects of exposure, transformation, and elimination. The course is designed for biology, chemistry, and pharmacy majors. Prerequisite requirements for this course may also be satisfied by equivalent course work as approved by the department.  
2 credits  
Prerequisites
min grade of C in BISC 1600 and BISC 1620 and CHEM 2210 and CHEM 2220 and 24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3480:   Principles of Life Sci. Res.  
Biomolecular Sciences  
This course addresses a broad spectrum of activities associated with the conduct of life science research. Students should gain a thorough understanding of the requirements, expectations and responsibilities of life science researchers.  
1 credit  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3510:   Drugs and Human Performance  
Biomolecular Sciences  
This course encompasses an analysis of the pharmacological, historical, religious, ethical, legal, and administrative considerations related to the use of drugs or supplements for the nontherapeutic purpose of enhancing cognitive, sexual, or physical performance. The primary goal of the course is to develop an in-depth appreciation of the factors associated with the nontherapeutic (off-label) use of substances to enhance human performance. More specifically, the course will enable a better understanding of the pharmacological as well as onpharmacological factors associated with such use. This course, unlike a typical "drug abuse" course, will not consider the use of substances to produce a "high" or altered state of consciousness, e.g., a positive or negative euphoria. Rather, the emphasis will be on the use of substances (including some controlled drugs) to improve human performance. Z grade.  
2 credits  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3520:   Case Studies in Immunology  
Biomolecular Sciences  
The designed elective course will provide students with an overview of the diseases of the immune system, particularly of genetically inherited primary immune deficiency diseases and an insight into the functioning of the normal immune system. Moreover, this course will also illustrate the interdisciplinary mechanisms of immunity, its clinical context, and describe the immunological problems often seen in the clinics. The course is designed for two kinds of students: those specializing in other areas and want to learn enough immunology to gain access to the experimental literature and those with a particular interest in immunology as preparation for an advanced immunology course.  
2 credits  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3810:   Introduction to Toxicology  
Biomolecular Sciences  
3 credits  
Prerequisites
min grade of C in CHEM 2220 and CHEM 2221 and 24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3820:   Fundamentals of Cancer  
Biomolecular Sciences  
Discussions of fundamental, underlying biological changes from normal physiology to cancer. Will include discussions of the cell cycle, cancer genetics, regulation of expression, carcinogenesis, metastasis and more to encompass an understanding of all concerns when considering treatment options in subsequent courses.  
2 credits  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 3999A:   Spec.ized Top. in Environ. Hlt  
Biomolecular Sciences  
In this course we will have focused, in-depth discussion of timely issues related to environmental health. Students will be informed of the issues through reading scientific literature and will be expected to propose solutions through discussion and writing assignments. Topics will be dictated by current events but could include, for example, environmental lead exposure and toxicity, pharmaceuticals in the environment, consequences of climate change, contamination of the food supply, e-waste etc.  
3 credits  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 4400:   Physiologic Case Stdy for Tx.  
Biomolecular Sciences  
The course focuses on problems based physiologic study of organ function and an emphasis on human physiology. The structure and function of the major body systems will be explored including the musculoskeletal, cardiovascular, respiratory, renal, nervous, endocrine, and body fluids and electrolytes.  
1 credit  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 4410:   Pharm.: Nov. Drugs in Clin Tri  
Biomolecular Sciences  
An in-depth discussion of topics of current importance in pharmacology of commonly occurring diseases is emphasized. Students learn about medicines currently in clinical trials and therapies in development.  
2 credits  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 4420:   Clinical Toxicology  
Biomolecular Sciences  
This course is designed to apply basic pharmacological and toxicological principles to the management of poisoned patients. Several of the drugs commonly encountered in accidental or intentional poisoning are to be covered. The student should be able to recognize signs and symptoms of poisoning, characterize the type and extent of intoxication, and develop a specific management plan.  
2 credits  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 4431:   Basic and Clinical Pharm. I  
Biomolecular Sciences  
Basic principles of pharmacodynamics; pharmacology of drugs acting on the autonomic nervous system; other drug classes acting on autonomic- innervated organs.  
4 credits  
Prerequisites
min grade of C in PHCL 3411 and PHCL 3412 and 24 earned credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
Course Fees:
$10.00
  
PHCL 4432:   Basic and Clinical Pharm. II  
Biomolecular Sciences  
Continuation of 443; central nervous system drugs; hematopoietic, immunosuppressant, antineoplastic, and antiallergic drugs; basics of environmental and clinical toxicology.  
4 credits  
Prerequisites
min grade of C in PHCL 4431 and 24 earned credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 4450:   Nutritional Pharmacology  
Biomolecular Sciences  
Discussions of how drugs, nutrients, and disease states interact and affect one another, how nutritional supplements influence drug therapy, nutritional status, and disease processes.  
1 credit  
Prerequisites
24 Earned Credits.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5010:   Principles of Life Sci. Res.  
Biomolecular Sciences  
This course consists of facilitated discussions of different topics. Students will be assigned as discussion facilitators for one or two topics. Student facilitators will be responsible for preparing a synopsis of the discussion for distribution to the class and for grading purposes. Grading will be 50 percent based on the discussion facilitation and write-up and 50 percent based on participation in other discussions.  
1 credit  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5031:   Lab Meth in Pharm. & Tox. I  
Biomolecular Sciences  
Fundamental laboratory exercises designed to provide the student with hands-on experience with techniques basic to the disciplines of pharmacology and toxicology.  
2 credits  
Potentially offered with the following Instruction Type(s):
Laboratory
  
PHCL 5032:   Lab Meth in Pharm. & Tox. II  
Biomolecular Sciences  
Fundamental laboratory exercises designed to provide the student with hands-on experience with techniques basic to the disciplines of pharmacology and toxicology.  
2 credits  
Prerequisites
min grade of C in PHCL 5031.
  
Potentially offered with the following Instruction Type(s):
Laboratory
  
PHCL 5050:   Mod. Phcl: Nov. Drugs Clin. Tr  
Biomolecular Sciences  
An in-depth discussion of topics of current importance in pharmacology of commonly occurring diseases are emphasized.  
2 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5131:   Introductory Pharmacology I  
Biomolecular Sciences  
General principles of pharmacodynamics; drugs affecting the autonomic nervous system and those organs innervated by that system. Prerequisite requirements for this course may also be satisfied by equivalent course work as approved by the department or by consent of instructor.  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5132:   Introductory Pharmacology II  
Biomolecular Sciences  
Continuation of 563; autonomic, cardiovascular, and renal drugs; endocrinological and chemotherapeutic agents. Prerequisite requirements for this course may also be satisfied by consent of instructor.  
4 credits  
Prerequisites
min grade of C in PHCL 5131.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5190:   Drug Abuse Education  
Biomolecular Sciences  
Pharmacological, legal, and socio-psychological aspects of drug abuse. Z grade  
3 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5360:   Receptors and Channels  
Biomolecular Sciences  
The course will cover aspects of cell signaling and membrane biophysics focused on inter and intracellular communication. Research techniques as well as classical and recent works will be discussed.  
3 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5381:   Introduction to Toxicology  
Biomolecular Sciences  
Course provides an introduction to the principles of toxicology.  
3 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5410:   Problems in Pharmacology  
Biomolecular Sciences  
Investigation of individual problems. (May be repeated for credit).  
1 - 3 credits  
Potentially offered with the following Instruction Type(s):
Independent Study
  
PHCL 5470:   Intro. to Envir. Toxicology  
Biomolecular Sciences  
Introduction to chemical nature and reactions of toxic substances, their origins and uses; and aspects of exposure, transformation, and elimination.  
2 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5510:   Principles of Life Sci. Res.  
Biomolecular Sciences  
This course consists of facilitated discussions of different topics. Students will be assigned as discussion facilitators for one or two topics. Student facilitators will be responsible for preparing a synopsis of the discussion for distribution to the class and for grading purposes. Grading will be 50 percent based on the discussion facilitation and write-up and 50 percent based on participation in other discussions.  
1 credit  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5531:   Lab Meth in Pharm. & Tox. I  
Biomolecular Sciences  
Fundamental laboratory exercises designed to provide the student with hands-on experience with techniques basic to the disciplines of pharmacology and toxicology.  
2 credits  
Potentially offered with the following Instruction Type(s):
Laboratory
  
PHCL 5532:   Lab Meth in Pharm. & Tox. II  
Biomolecular Sciences  
Fundamental laboratory exercises designed to provide the student with hands-on experience with techniques basic to the disciplines of pharmacology and toxicology.  
2 credits  
Prerequisites
min grade of C in PHCL 5031.
  
Potentially offered with the following Instruction Type(s):
Laboratory
  
PHCL 5550:   Mod. Phcl: Nov. Drugs Clin. Tr  
Biomolecular Sciences  
An in-depth discussion of topics of current importance in pharmacology of commonly occurring diseases are emphasized.  
2 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5631:   Introductory Pharmacology I  
Biomolecular Sciences  
General principles of pharmacodynamics; drugs affecting the autonomic nervous system and those organs innervated by that system. Prerequisite requirements for this course may also be satisfied by equivalent course work as approved by the department or by consent of instructor.  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5632:   Introductory Pharmacology II  
Biomolecular Sciences  
Continuation of 563; autonomic, cardiovascular, and renal drugs; endocrinological and chemotherapeutic agents. Prerequisite requirements for this course may also be satisfied by consent of instructor.  
4 credits  
Prerequisites
min grade of B in PHCL 5631.
  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5690:   Drug Abuse Education  
Biomolecular Sciences  
Pharmacological, legal, and socio-psychological aspects of drug abuse. Z grade  
3 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5860:   Receptors and Channels  
Biomolecular Sciences  
The course will cover aspects of cell signaling and membrane biophysics focused on inter and intracellular communication. Research techniques as well as classical and recent works will be discussed.  
3 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5881:   Introduction to Toxicology  
Biomolecular Sciences  
Course provides an introduction to the principles of toxicology.  
3 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 5910:   Problems in Pharmacology  
Biomolecular Sciences  
Investigation of individual problems. (May be repeated for credit).  
1 - 3 credits  
Potentially offered with the following Instruction Type(s):
Independent Study
  
PHCL 5970:   Intro. to Envir. Toxicology  
Biomolecular Sciences  
Introduction to chemical nature and reactions of toxic substances, their origins and uses; and aspects of exposure, transformation, and elimination.  
2 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 6110:   Tching in Pharm. and Tox.  
Biomolecular Sciences  
Graduate students will be carefully monitored in their teaching activities in undergraduate pharmacy courses. Z grade  
1 credit  
Potentially offered with the following Instruction Type(s):
Seminar
  
PHCL 6120:   Tching in Pharm. and Tox.  
Biomolecular Sciences  
Graduate students will be carefully mentored in their teaching activities in undergraduate pharmacy courses. Z grade  
1 credit  
Potentially offered with the following Instruction Type(s):
Seminar
  
PHCL 6410:   Unif Lab in Pharm, Tox & Phys  
Biomolecular Sciences  
Unified laboratory in pharmacology, toxicology, and physiological chemistry. Fundamental experiments illustrating concepts common to the three disciplines; both in vivo and in vitro techniques will be utilized.  
2 credits  
Potentially offered with the following Instruction Type(s):
Laboratory
  
PHCL 6420:   Unif Lab in Pharm, Tox & Phys  
Biomolecular Sciences  
Unified laboratory in pharmacology, toxicology, and physiological chemistry. Fundamental experiments illustrating concepts common to the three disciplines; both in vivo and in vitro techniques will be utilized.  
2 credits  
Potentially offered with the following Instruction Type(s):
Laboratory
  
PHCL 6430:   Sem: Curr Top. in Pharm & Tox  
Biomolecular Sciences  
Z grade  
1 credit  
Potentially offered with the following Instruction Type(s):
Seminar
  
PHCL 6510:   Directed St. in Pharm and Tox  
Biomolecular Sciences  
Research tutorials requiring individual conferences, literature assignments, and laboratory experiences with departmental faculty members.  
1 credit  
Potentially offered with the following Instruction Type(s):
Independent Study
  
PHCL 6520:   Directed St. in Pharm and Tox  
Biomolecular Sciences  
Research tutorials requiring individual conferences, literature assignments, and laboratory experiences with departmental faculty members. Z grade  
1 credit  
Potentially offered with the following Instruction Type(s):
Independent Study
  
PHCL 6610:   Advanced Physiology  
Biomolecular Sciences  
Physiology of those systems, organs, and physiological mechanisms of special significance to pharmacology, including a comparative cross-species emphasis for selected organ systems. Prerequisite requirements for this course may also be satisfied by consent of instructor.  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture/Lab
  
PHCL 6620:   Advanced Physiology  
Biomolecular Sciences  
Physiology of those systems, organs, and physiological mechanisms of special significance to pharmacology, including a comparative cross-species emphasis for selected organ systems. Prerequisite requirements for this course may also be satisfied by consent of instructor.  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture/Lab
  
PHCL 6630:   General Pharmacology I  
Biomolecular Sciences  
Fundamentals of pharmacokinetic, pharmacodynamic, and receptor selectivity of various classes of biologically active agents.  
3 credits  
Potentially offered with the following Instruction Type(s):
Lecture/Lab
  
PHCL 6650:   Human Neurobiology  
Biomolecular Sciences  
Review of the neuroanatomical, neurophysiological, and neurochemical substances upon which centrally acting drugs and toxicants may act.  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture/Lab
  
PHCL 6680:   Externship in Pharmacology  
Biomolecular Sciences  
Credit given for participation in pharmacological screening procedures carried out in the laboratories of a pharmaceutical manufacturer. Z grade  
1 - 8 credits  
Potentially offered with the following Instruction Type(s):
Internship
  
PHCL 6690:   Physiological Chemistry  
Biomolecular Sciences  
Carbohydrate, protein, and nucleic acid structure and function, enzyme catalysis, intermediary metabolism, biochemical endocrinology, membrane structure, mechanisms of solute transport, and molecular genetics.  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 6751:   Gen Princ of Pharm. & Tox. I  
Biomolecular Sciences  
General principles of pharmacology and toxicology; biotransformation of toxicants; chemical carcinogenesis, mutagenesis, teratogenesis; receptors and signaling pathways. Prerequisite requirements for this course may also be satisfied by consent of instructor.  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 6752:   Gen Princ - Pharm. & Tox. II  
Biomolecular Sciences  
General principles of pharmacology and toxicology, drug toxicology, organ systems, risk assessment, environmental toxicants. Prerequisite requirements for this course may also be satisfied by consent of instructor.  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 6790:   Meth. in Pharm. and Toxicology  
Biomolecular Sciences  
Emphasis on the quantification of toxic responses of chemical origin. Use of toxicology in the regulatory process; principles and methods for acute and chronic toxicity; biochemical methods for reassessing organ function; reproductive toxicity testing; risk assessment of chemical hazards. (Lecture and laboratory).  
4 credits  
Potentially offered with the following Instruction Type(s):
Lecture/Lab
  
PHCL 6810:   Sel Top. - Pharm. and Tox.  
Biomolecular Sciences  
Topics may include pharmacokinetic, pharmacodynamic, and receptor selectivity of biologically active agents, food additives, drug toxicity, toxicology of agricultural and industrial chemicals, clinical toxicology, toxicity of plastics; naturally occurring toxins.  
2 credits  
Potentially offered with the following Instruction Type(s):
Lecture
  
PHCL 6850:   Externship in Toxicology  
Biomolecular Sciences  
Credit given for research performed in toxicology at other academic institutions or private industrial concerns. Z grade  
1 - 8 credits  
Potentially offered with the following Instruction Type(s):
Internship
  
PHCL 6999A:   Advanced Topics  
Biomolecular Sciences  
Lectures, readings, and discussions of special areas of experimental pharmacology and allied subjects. (May be repeated for credit).  
2 credits  
Potentially offered with the following Instruction Type(s):
Independent Study