Medicinal Chemistry (MEDC)
MEDC 3170: Pharmagenet. and Pharmaimmuno.
Biomolecular Sciences
A detailed introduction to the basic concepts of molecular genetics, biotechnology, and immunology of life processes that provide an essential foundation for rational drug therapy.
3 credits
Prerequisites
24 Earned Credits.
24 Earned Credits.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 3180: Chem. and Biological Terrorism
Biomolecular Sciences
chemical, biological, radiological and nuclear terrorism poses a considerable threat throughout the world. The expectation of chemical, biological, radiological and/or nuclear violence is recognized as an acute security challenge. The likelihood, over time, of terrorist organizations coming into possession of such unconventional materials, and their use against the Unites States homeland, is tremendously elevated. The combination of increasing availability of technology and expertise, a mass-casualty attack may be inevitable.
2 - 3 credits
Prerequisites
CHEM 1010 and 24 Earned Credits.
CHEM 1010 and 24 Earned Credits.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 3190: Computer-Aided Drug Design
Biomolecular Sciences
The student will learn to utilize state-of-the-art commercial software to conduct Computer-Aided Structure Based Drug Design (CADD). De novo design will be conducted after database screening (aka database mining, virtual screening) as a method to invent small molecules that bind to the active site(s) of protein X-ray structures. The course will involve discussion of protein molecules, X-ray crystallography produced structures of proteins or protein-ligand complexes, molecular interactions that are either attractive or repulsive in nature, and computer software for visualization, manipulation, and energy calculations.
2 credits
Prerequisites
24 Earned Credits.
24 Earned Credits.
Potentially offered with the following Instruction Type(s):
Lecture/Lab
Lecture/Lab
MEDC 4150: Chem. Neurosci. Prin. of Drug
Biomolecular Sciences
This course will cover the Chemical Neuroscience Principles of Drug Abuse including, but not limited to, neurochemistry, neuropharmacology, toxicology, and pharmacotherapy.
1 credit
Prerequisites
(min grade of C in PHCL 4431 and MEDC 4161) and (one way co-requisites in PHCL 4432 and MEDC 4162) and 24 Earned Credits.
(min grade of C in PHCL 4431 and MEDC 4161) and (one way co-requisites in PHCL 4432 and MEDC 4162) and 24 Earned Credits.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 4161: Intro- Princ. of Med Chem I
Biomolecular Sciences
Introduction to the chemical and physical properties of medicinal agents, relationships of structural properties of drugs to pharmacological properties and metabolism profiles, chemical stability, mechanism of action and clinically significant chemical interactions.
3 credits
Prerequisites
24 Earned Credits.
24 Earned Credits.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
Course Fees:
$15.00
$15.00
MEDC 4162: Intro- Princ. of Med Chem II
Biomolecular Sciences
A continuation of the introduction to the chemical and physical properties of medicinal agents, relationships of structural properties of drugs to pharmacological properties and metabolism profiles, chemical stability, mechanism of action and clinically significant chemical interactions.
3 credits
Prerequisites
MEDC 4161 and 24 Earned Credits.
MEDC 4161 and 24 Earned Credits.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 4180: Neuro. Princ. of Drug Abuse
Biomolecular Sciences
The content of this course focuses on a fundamental understanding of the chemical and physiochemical properties of drugs of abuse and chemical dependency as it relates to the practice of pharmacy.
1 credit
Prerequisites
24 Earned Credits.
24 Earned Credits.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 4999A: Special Topics in Oncology
Biomolecular Sciences
This course is designed for students to engage in advanced discussions of oncological therapeutic topics to increase their knowledge about the ideology, clinical presentation and management of various solid and hematological maligancies.
1 credit
Prerequisites
24 Earned Credits.
24 Earned Credits.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 5011: Advanced Medicinal Chemistry I
Biomolecular Sciences
Advanced study of organic medicinal agents with emphasis on names, synthesis, chemical properties, and pharmacological properties. Readings in the current literature required.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 5012: Advanced Med. Chemistry II
Biomolecular Sciences
Continuation of Medicinal Chemistry 501. Readings in the current literature required. Prerequisite requirements for this course may also be satisfied by consent of department.
3 credits
Prerequisites
min grade of C in MEDC 5011.
min grade of C in MEDC 5011.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 5030: Med. Chemistry Res. Method
Biomolecular Sciences
A hands-on introduction to the practical aspects of the chemical methodology necessary to conduct medicinal chemistry research, including separation and purification technology, spectroscopic techniques, and medicinal chemistry literature searching.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture/Lab
Lecture/Lab
MEDC 5070: Organic Chem. of Drug Synth
Biomolecular Sciences
Discussion of the synthetic approaches to many of the therapeutic classes of drugs studied in medicinal chemistry courses with an accent on the relationship of chemical structure to improved efficacy. Prerequisite requirements for this course may also be satisfied by consent of department.
3 credits
Prerequisites
min grade of C in MEDC 5011.
min grade of C in MEDC 5011.
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 5410: Prob. in Medicinal Chemistry
Biomolecular Sciences
Investigation of individual problems.
1 - 4 credits
Potentially offered with the following Instruction Type(s):
Independent Study
Independent Study
MEDC 5420: Prob. in Medicinal Chemistry
Biomolecular Sciences
Investigation of individual problems.
1 - 4 credits
Potentially offered with the following Instruction Type(s):
Independent Study
Independent Study
MEDC 5511: Advanced Medicinal Chemistry I
Biomolecular Sciences
Advanced study of organic medicinal agents with emphasis on names, synthesis, chemical properties, and pharmacological properties. Readings in the current literature required.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 5512: Advanced Med. Chemistry II
Biomolecular Sciences
Continuation of Medicinal Chemistry 501. Readings in the current literature required. Prerequisite requirements for this course may also be satisfied by consent of department.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 5530: Med. Chemistry Res. Method
Biomolecular Sciences
A hands-on introduction to the practical aspects of the chemical methodology necessary to conduct medicinal chemistry research, including separation and purification technology, spectroscopic techniques, and medicinal chemistry literature searching.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture/Lab
Lecture/Lab
MEDC 5570: Organic Chem. of Drug Synth
Biomolecular Sciences
Discussion of the synthetic approaches to many of the therapeutic classes of drugs studied in medicinal chemistry courses with an accent on the relationship of chemical structure to improved efficacy. Prerequisite requirements for this course may also be satisfied by consent of department.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 5910: Prob. in Medicinal Chemistry
Biomolecular Sciences
Investigation of individual problems.
1 - 4 credits
Potentially offered with the following Instruction Type(s):
Independent Study
Independent Study
MEDC 5920: Prob. in Medicinal Chemistry
Biomolecular Sciences
Investigation of individual problems.
1 - 4 credits
Potentially offered with the following Instruction Type(s):
Independent Study
Independent Study
MEDC 6300: Pharma. Protein Design & Devel
Biomolecular Sciences
This course focuses on the chemical and structural characteristics of protein pharmaceuticals, which make them different from conventional pharmaceutical products.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 6999A: Selected Topics in Med. Chem.
Biomolecular Sciences
Recent advances emphasizing mechanisms of drug action and other new concepts. (May be repeated for credit).
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 7110: Intro to Comp.-Aided Drug Des.
Biomolecular Sciences
Modern molecular modeling methods and techniques pertinent to molecular design and the simulation of molecular properties and interactions. Examples include modeling of small molecules at the level of mechanics calculations up to ab initio calculations; homology modeling of proteins and related validation methods; docking interactions of ligands and receptors.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture/Lab
Lecture/Lab
MEDC 7120: QSAR & AI for Drug Design
Biomolecular Sciences
QSAR and Artificial Intelligence for Drug Design. The basics and application of Quantitative Structure-Activity Relation (QSAR and 3D- QSAR) and artificial intelligence (AI), and other related ligand-based drug design computational approaches, such as ADMET prediction, pharmacophore modeling, and virtual screening.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture/Lab
Lecture/Lab
MEDC 7130: Drugs Affecting the Nervous Sy
Biomolecular Sciences
Discussion and application of the design, synthesis, and biological activities of drugs affecting both the central and peripheral nervous system.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 7140: Chemotherapeutic Agents
Biomolecular Sciences
Overview of anticancer, antimicrobial and antiviral chemotherapy as related to drug design, chemical syntheses, structural classes, mechanisms of pharmacological action, toxicities, resistance mechanisms and clinical usefulness.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture
MEDC 7180: Bioorganic Chemistry
Biomolecular Sciences
The study of the chemical interactions and catalytic strategies fundamental to drug design and development, using the principles of organic chemistry as the intellectual framework for addressing biological problems at the molecular level.
3 credits
Potentially offered with the following Instruction Type(s):
Lecture
Lecture