Phcg 426: Cancer Chemo - Targets and Discovery
MEDICINAL CHEMISTRY
This course provides a general synopsis of the discovery and development of anticancer chemotherapeutics, with particular emphasis on those that are derived from natural products. The course includes discussions of the critical molecular and/or cellular events underlying the etiology and progression of cancer, anticancer target selection and validation, bioassay methods, screening libraries of compounds and/or extracts, bioassay-guided isolation and structure elucidation, and biological characterization/evaluation of active leads. Examples from four focus areas will be studied and discussed: cytotoxic agents, targeted therapies, tumor metabolism, and antimetastasis drug discovery.
2 Credits
Prerequisites
- Phcl 341: Human Pathophysiology I
- Phcl 342: Human Pathophysiology II
- Pre-requisite: Pharmacy PY2
Instruction Type(s)
- Lecture: Lecture for Phcg 426
Subject Areas
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